Price shown is per month for the plan length selected. Planned prices; the final amount is always shown at checkout before you pay.
Recurring plans renew automatically at the end of each plan length until you cancel; a single order does not renew. You can cancel anytime from the patient portal, with no cancellation fee. See the plan renewal terms.
The FDA does not review or approve compounded medications for safety, effectiveness or quality. Compounded naltrexone hydrochloride (compounded) is not a generic version of, or equivalent to, any branded medication.
Packaging illustration. Your pharmacy label provides your prescribed directions; do not use this image for dosing.
No outcome is guaranteed. Individual results vary.
Longevity & Healthy AgingCompounded · Oral · Rx only
Naltrexone
Support for your alcohol-use goals.
Naltrexone is a prescription medicine approved for alcohol dependence as part of a treatment plan, and also prepared by compounding pharmacies at low doses for other, off-label uses. It is prescribed online only if a licensed provider decides it is right for you after reviewing your health history and current medicines.
Naltrexone: support for your alcohol-use goals. If a licensed provider prescribes it as part of a personalized treatment plan, naltrexone:
May help reduce alcohol cravings
May help reduce alcohol cravings.
May lessen alcohol's reward
May lessen the rewarding effects of alcohol.
May help reduce consumption
May help reduce alcohol consumption as part of a personalized treatment plan.
Guided by a licensed provider
Prescription treatment is guided by a licensed healthcare provider.
Explore your options: connect with a provider to learn whether naltrexone may be appropriate for you. Individual results vary; benefits are not guaranteed.
Why it matters
What is known about naltrexone
Naltrexone has been prescribed for alcohol dependence for decades; at low doses it is also studied for other conditions. Here is what is known, plainly.
What the evidence covers
Alcohol dependence: an FDA-approved use, as part of a treatment plan
Low-dose use: small studies in fibromyalgia, Crohn's disease and long-lasting pain
What your provider checks first
Any opioid medicine, including for pain
Liver health and alcohol use
Mood history and current mental health care
Pregnancy, plans for pregnancy or breastfeeding
Naltrexone is one part of a plan, not a stand-alone solution; studies of low-dose use are small. A licensed provider reviews your history before deciding whether it is appropriate for you.
Understanding Naltrexone
What to know first.
Regulatory status
Naltrexone tablets are FDA-approved for the treatment of alcohol dependence and for blocking the effects of opioids, as part of a broader program. Low-dose naltrexone is a compounded preparation at a much lower strength; it is not FDA-approved, and the FDA does not review compounded medicines for safety, effectiveness or quality.
How it works
Naltrexone blocks opioid receptors. At the low strengths used in LDN, the blockade is thought to be short and partial. Two ideas are studied: a brief blockade may lead the body to make more of its own endorphins, and naltrexone may calm certain immune cells in the nervous system (through a receptor called TLR4) that take part in inflammation. These are working explanations, not settled facts, and how any one person responds varies.
Who it may be for
A provider may consider low-dose naltrexone for some adults with long-standing inflammatory or pain-related symptoms, after reviewing their history and every medicine they take. It is not for anyone taking opioid medicines or in opioid withdrawal, anyone with acute hepatitis or liver failure, or anyone allergic to naltrexone. Your provider decides.
Off-label use. Low-dose naltrexone is not FDA-approved for inflammatory or pain-related conditions, fatigue or wellness; prescribing it for those purposes is off-label and decided by your provider.
How it works
Three steps, all online.
01
Complete your online visit
Answer questions about your health history, medications and goals. Submitting a visit does not guarantee a prescription.
02
A licensed provider reviews
A provider licensed in your state decides whether treatment is appropriate for you, or recommends a different path.
03
If prescribed, delivered
A licensed pharmacy dispenses your medication and ships it to your door. Follow-up continues through the patient portal.
Plans & prices
Naltrexone price by plan.
Prices in US dollars. Self-pay; insurance is not required.
Plan length
Per month
Billed at checkout
Supply
Single order
$125 once
$125 single payment, no renewal
One-month supply
Monthly
$125/mo
$125 billed every month
One-month supply
Planned prices; the final amount is always shown at checkout before you pay. See the Terms of Service and Refund Policy.
What is the difference between naltrexone and low-dose naltrexone?
Naltrexone tablets are an FDA-approved medicine for alcohol dependence and for blocking the effects of opioids. Low-dose naltrexone is the same molecule prepared by a compounding pharmacy at a much lower strength, used off-label for other purposes. The compounded preparation is not FDA-approved, and the FDA does not review it for safety, effectiveness or quality.
Is low-dose naltrexone FDA-approved for inflammation or pain?
No. Its use for inflammatory or pain-related conditions, fatigue or wellness is off-label. Once a drug is approved, providers generally may prescribe it for an unapproved use when they judge it appropriate for a patient, although the FDA has not found it safe and effective for that use. Your provider makes that decision for you.
How is it thought to work?
Naltrexone blocks opioid receptors. At low strengths the blockade is thought to be brief and partial, which may prompt the body to make more of its own endorphins, and naltrexone may also calm immune cells in the nervous system that take part in inflammation. Both are working explanations from small studies, and how any one person responds varies.
Can I take it if I use opioid pain medicines?
No. Naltrexone blocks opioid medicines and can trigger withdrawal in anyone who depends on them. Tell your provider about every medicine you take, including opioid pain relievers, cough medicines and treatments for opioid use disorder. Your provider screens for this before prescribing.
What side effects should I know about?
In studies of low-dose naltrexone, the most common effects were sleep changes such as vivid dreams, headache, and stomach upset, usually mild. The approved tablet's label lists nausea, headache, dizziness, nervousness, tiredness and trouble sleeping. Tell your provider about anything that worries you, and read the Important Safety Information below.
How does the online visit work?
You complete a health assessment online and a licensed provider reviews your answers, history and current medicines. If they decide low-dose naltrexone is appropriate, a licensed compounding pharmacy prepares it and ships it to you. Forever Health Rx is a telemedicine platform, not a pharmacy, and completing an assessment or paying does not mean you will receive a prescription. Not everyone qualifies, and individual results vary.
Important Safety Information — Naltrexone
Compounded drug notice
Compounded low-dose naltrexone is prepared by a state-licensed pharmacy for an individual patient. It is not FDA-approved, the FDA does not review compounded medicines for safety, effectiveness or quality, and it is not a generic version of, or equivalent to, any approved product.
Regulatory status
Naltrexone tablets are FDA-approved for the treatment of alcohol dependence and for blocking the effects of opioids, as part of a broader program. Low-dose naltrexone is a compounded preparation at a much lower strength; it is not FDA-approved, and the FDA does not review compounded medicines for safety, effectiveness or quality.
Off-label use. Low-dose naltrexone is not FDA-approved for inflammatory or pain-related conditions, fatigue or wellness; prescribing it for those purposes is off-label and decided by your provider.
Do not use if
Currently taking opioid medicines, including pain relievers, some cough medicines, methadone or buprenorphine
In acute opioid withdrawal, or if you have used opioids in the days before starting (your provider sets the interval)
Acute hepatitis or liver failure
Known allergy to naltrexone or any ingredient in the preparation
Before starting, tell your provider if
Any history of opioid use, opioid use disorder or treatment for it
Liver disease, heavy alcohol use or abnormal liver tests
Kidney disease
Depression, thoughts of self-harm, or any mental health condition
Pregnancy, plans to become pregnant, or breastfeeding
Every medicine, supplement and sleep aid you take
Serious side effects — get medical help right away
Precipitated opioid withdrawal. In anyone physically dependent on opioids, naltrexone can trigger sudden, severe withdrawal. Get medical help right away for severe stomach cramps, vomiting, diarrhea, sweating, agitation or a racing heart after a dose.
Blocked pain relief in an emergency. Naltrexone blocks opioid pain medicines. Carry a note or card saying you take naltrexone so emergency teams can plan pain control; attempts to overcome the block with large opioid doses can be fatal.
Liver injury. The approved tablet's label reports liver test changes at higher strengths. Get help right away for yellowing skin or eyes, dark urine, pale stools, severe stomach pain or unusual tiredness.
Mood changes. Depression and thoughts of self-harm have been reported in people taking naltrexone. Tell your provider right away about any change in mood; in a crisis, call or text 988.
Allergic reaction. Get help right away for rash, swelling of the face or throat, or trouble breathing.
Common side effects
Common side effects: nausea, headache, dizziness, nervousness, tiredness, trouble sleeping or vivid dreams, and stomach upset. These are not all the possible side effects.
You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Pregnancy and breastfeeding
The safety of naltrexone in pregnancy and breastfeeding has not been established; naltrexone and its metabolite pass into breast milk. Tell your provider if you are pregnant, planning a pregnancy or breastfeeding.
If you need surgery or emergency care, tell the care team you take naltrexone.
Forever Health Rx does not provide emergency or crisis care. In an emergency call 911; for a mental health crisis call or text 988.
Prescription only. Naltrexone is available only after an online visit with a licensed provider, who determines whether treatment is appropriate for you. This summary does not replace the full prescribing information. Not medical advice. Results may vary.
Forever Health Rx does not provide emergency medical care. Call 911 or go to the nearest emergency department if you are experiencing a medical emergency. For urgent questions about a serious side effect, message your care team through the patient portal and seek in-person care if symptoms are severe.
Your next step
Start with a free online visit.
About ten minutes. A licensed provider reviews your information and decides whether treatment is right for you.
Have a question before you start? Call our support team:
Prescription required. Eligibility is determined by a licensed provider. Not medical advice. Results may vary.
Important safety & regulatory information
Please read before you start.
Forever Health Rx is a healthcare technology platform operated by . Forever Health Rx is not a pharmacy and does not practice medicine. Medical services are provided by independent, state-licensed healthcare providers of , who exercise their own clinical judgment. Prescriptions are issued only after a provider reviews your information and determines that treatment is appropriate for you. Not everyone qualifies, and no treatment, outcome or eligibility is guaranteed.
Some medications referenced on this site are compounded preparations prepared by U.S. pharmacies licensed in the state where they dispense. Compounded drugs are not approved by the FDA and are not evaluated by the FDA for safety, effectiveness or quality. They are not generic versions of, or equivalent to, any branded medication. Other medications referenced are FDA-approved products, described only for their FDA-approved uses unless a page states that a use is off-label. Brand names are trademarks of their respective owners; Forever Health Rx is not affiliated with them.
Every prescription medication carries risks. Product-specific warnings, contraindications and side effects are listed in the safety information on each treatment page; discuss your full medical history and every medication you take with your provider. Treatments shown as coming soon are not yet available for purchase, and their prices may be estimates.
This website does not provide medical advice and is not a substitute for consultation with a qualified clinician. In an emergency, call 911. To report a side effect, contact your provider through the patient portal or the FDA MedWatch program at 1-800-FDA-1088.
Weight figures, timelines and projections shown anywhere on this site are illustrative and drawn from published clinical literature, not from Forever Health Rx patient outcomes. Individual results vary.
Your provider confirms the plan and its cost after review. Payment collected at checkout is refunded in full if a prescription is not issued, and nothing is dispensed. The final amount is always shown at checkout before you authorize payment.
This website collects no protected health information; your online visit, prescriptions and messages take place inside the secure patient portal, covered by our HIPAA Privacy Policy.
People pictured on this site are illustrative images, not Forever Health Rx patients. They do not describe anyone's treatment experience and do not depict the results of any medication. Product images are illustrative; actual packaging may vary.