Women's HealthFDA-approved · Oral capsule · Rx only
Progesterone
Protecting the uterus during estrogen therapy
Micronized progesterone capsules are an FDA-approved hormone used in postmenopausal women who still have a uterus and take estrogen, and for secondary amenorrhea (periods that have stopped). They are prescribed online only if a licensed provider decides they are right for you after reviewing your health history.
Coming soon to Forever Health Rx. Not available for purchase yet. Prices shown are estimates and may change.
Micronized progesterone is an FDA-approved oral capsule; if a licensed provider prescribes it, it may help with:
Protects the uterine lining
Approved to prevent overgrowth of the uterine lining in postmenopausal women on estrogen who still have a uterus.
Periods that have stopped
Approved to treat secondary amenorrhea, menstrual periods that have stopped in a woman who had them before.
Counters estrogen's effect
Works by countering the way estrogen on its own stimulates the lining of the uterus to grow.
Provider sets the dose
Your provider sets the dose and reviews your health history, including any peanut allergy.
Licensed pharmacy ships it
If prescribed, a licensed pharmacy dispenses your capsules and ships them to you.
Not medical advice. Individual results vary. A licensed provider decides whether a treatment is right for you.
Understanding Progesterone
What to know first.
Approved use
Progesterone capsules are FDA-approved for the prevention of endometrial hyperplasia (overgrowth of the lining of the uterus) in postmenopausal women who have not had a hysterectomy and who are taking estrogen, and for the treatment of secondary amenorrhea (menstrual periods that have stopped in a woman who previously had them). This page discusses both uses.
How it works
Progesterone is the hormone the ovaries make in the second half of the menstrual cycle. Estrogen taken on its own stimulates the lining of the uterus to grow; progesterone counters that effect, which is why it is prescribed alongside estrogen for a woman who still has her uterus. In secondary amenorrhea it is used to treat periods that have stopped. How much it helps varies. These capsules contain micronized progesterone in peanut oil and are taken by mouth; the label says to take them at bedtime because some women become very drowsy or dizzy. Your provider sets the dose.
Who it may be for
A provider may consider progesterone capsules for a postmenopausal woman who still has her uterus and takes estrogen for menopause symptoms, or for an adult with secondary amenorrhea, after reviewing personal and family history. They are not for anyone allergic to peanuts, with unexplained vaginal bleeding, with known, suspected or past breast cancer, with current or past blood clots, stroke or heart attack, or with liver disease, and they should not be used during pregnancy. Your provider decides.
How it works
Three steps, all online.
01
Complete your online visit
Answer questions about your health history, medications and goals. Submitting a visit does not guarantee a prescription.
02
A licensed provider reviews
A provider licensed in your state decides whether treatment is appropriate for you, or recommends a different path.
03
If prescribed, delivered
A licensed pharmacy dispenses your medication and ships it to your door. Follow-up continues through the patient portal.
Estrogen taken alone raises the risk of endometrial hyperplasia, an overgrowth of the uterine lining that can lead to uterine cancer. Progesterone capsules are FDA-approved to prevent that overgrowth in postmenopausal women who still have a uterus and are taking estrogen. A woman who has had a hysterectomy does not need it for this purpose. Your provider decides whether you need a progestogen and, if so, which one and at what dose.
Does progesterone carry a boxed warning?
The current FDA-approved label for progesterone capsules no longer has a boxed warning. In February 2026 the FDA approved removal of the cardiovascular disease, breast cancer and probable dementia statements from the boxed warnings of the first menopausal hormone therapy products, including a progesterone capsule product. The findings themselves remain in the label: the Women's Health Initiative reported increased risks of blood clots in the lungs and legs, stroke, heart attack and invasive breast cancer in postmenopausal women taking estrogen plus a progestin, and a higher risk of probable dementia in women 65 and older. Your provider weighs these risks with you.
Why does the label say to take it at bedtime?
Because some women become very drowsy or dizzy after taking progesterone capsules. The label says they may cause transient dizziness and drowsiness and should be used with caution when driving a motor vehicle, so taking them at bedtime limits that effect. Tell your provider if drowsiness or dizziness is strong or lasts into the day.
What if I am allergic to peanuts?
These capsules contain peanut oil, and the label says the product should not be used by anyone allergic to peanuts. Tell your provider about a peanut allergy or any other allergy before your assessment is reviewed; if a progestogen is still appropriate for you, your provider may discuss other options that do not contain peanut oil.
What should I report right away?
Unusual vaginal bleeding, which the label says to report to your health care provider right away. Also seek care for signs of a blood clot, stroke or heart attack (chest pain, calf pain, sudden shortness of breath, severe headache, weakness on one side, trouble speaking), for sudden partial or complete loss of vision, bulging of the eye, double vision or migraine, and for a new breast lump.
Do I still need in-person check-ups?
Yes. The patient information advises a pelvic exam, breast exam and mammogram every year. Forever Health Rx does not offer in-person visits, so this care happens with your own local health care professionals, and any unusual vaginal bleeding needs prompt in-person evaluation. Your provider can explain what is recommended for you.
How does the online visit work?
You complete a health assessment online and a licensed provider reviews your answers and history. If they decide progesterone is appropriate, a licensed pharmacy dispenses it. Forever Health Rx is a telemedicine platform, not a pharmacy, and completing an assessment or paying does not mean you will receive a prescription. Not everyone qualifies, and individual results vary.
Important Safety Information — Progesterone
What is it approved for?
Progesterone capsules are FDA-approved for the prevention of endometrial hyperplasia (overgrowth of the lining of the uterus) in postmenopausal women who have not had a hysterectomy and who are taking estrogen, and for the treatment of secondary amenorrhea (menstrual periods that have stopped in a woman who previously had them). This page discusses both uses.
Do not use if
Allergy to peanuts (the capsules contain peanut oil) or to any other ingredient
Abnormal vaginal bleeding whose cause has not been found
Known, suspected or past breast cancer
Current or past blood clots in the legs or lungs (deep vein thrombosis or pulmonary embolism)
Current or past arterial clotting disease, such as a stroke or heart attack
Known liver dysfunction or liver disease
Pregnancy (the label says progesterone capsules should not be used during pregnancy)
Before starting, tell your provider if
Whether you still have your uterus and whether you take estrogen
Any condition that fluid retention could worsen, such as heart or kidney problems, because the label says progesterone may cause some degree of fluid retention
Whether you drive or operate machinery, since the capsules may cause transient dizziness and drowsiness
Depression now or in the past (depression was reported as a side effect in clinical trials)
All medicines and supplements you take; the label notes that ketoconazole and other medicines that inhibit the same liver enzyme may increase progesterone levels
Breastfeeding (the label advises caution)
Serious side effects — get medical help right away
Blood clots, stroke and heart attack. The Women's Health Initiative reported increased risks of blood clots in the lungs and legs, stroke and heart attack in postmenopausal women taking estrogen plus a progestin. Get emergency help for chest pain, pain in your calves, sudden shortness of breath, a severe headache, weakness or numbness on one side, or trouble speaking.
Breast cancer. The same study reported an increased risk of invasive breast cancer with estrogen plus a progestin. Report any breast lump, and keep yearly breast exams and mammograms.
Probable dementia. In the WHI Memory Study, women 65 and older taking estrogen plus a progestin had an increased risk of developing probable dementia.
Vision problems. Blood clots in the retina have been reported. Stop and get prompt care for sudden partial or complete loss of vision, sudden bulging of the eye, double vision or migraine.
Unusual vaginal bleeding. See your health care provider right away if you get unusual vaginal bleeding while taking progesterone capsules.
Severe dizziness or drowsiness. Some women become very drowsy or dizzy. Take the capsules at bedtime as the label directs, do not drive if you feel affected, and tell your provider if it does not settle.
Common side effects
Common side effects reported in clinical trials: headache, breast tenderness or pain, joint or muscle pain, dizziness, drowsiness, depression, abdominal bloating or cramping, nausea, tiredness, vaginal yeast infection and cold-like symptoms. These are not all the possible side effects.
You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Pregnancy and breastfeeding
Progesterone capsules should not be used during pregnancy. The label advises caution when they are given to a woman who is breastfeeding, so tell your provider if you are nursing.
These capsules contain peanut oil and should not be used by anyone allergic to peanuts.
Prescription only. Progesterone is available only after an online visit with a licensed provider, who determines whether treatment is appropriate for you. This summary does not replace the full prescribing information. Not medical advice. Results may vary.
Forever Health Rx does not provide emergency medical care. Call 911 or go to the nearest emergency department if you are experiencing a medical emergency. For urgent questions about a serious side effect, message your care team through the patient portal and seek in-person care if symptoms are severe.
Coming soon
Be the first to know.
Progesterone is coming soon to Forever Health Rx. Contact us and we will let you know when it is available.
Have a question before you start? Call our support team:
Prescription required. Eligibility is determined by a licensed provider. Not medical advice. Results may vary.
Important safety & regulatory information
Please read before you start.
Forever Health Rx is a healthcare technology platform operated by . Forever Health Rx is not a pharmacy and does not practice medicine. Medical services are provided by independent, state-licensed healthcare providers of , who exercise their own clinical judgment. Prescriptions are issued only after a provider reviews your information and determines that treatment is appropriate for you. Not everyone qualifies, and no treatment, outcome or eligibility is guaranteed.
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This website does not provide medical advice and is not a substitute for consultation with a qualified clinician. In an emergency, call 911. To report a side effect, contact your provider through the patient portal or the FDA MedWatch program at 1-800-FDA-1088.
Weight figures, timelines and projections shown anywhere on this site are illustrative and drawn from published clinical literature, not from Forever Health Rx patient outcomes. Individual results vary.
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